Origin of Genes

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Evolutionary Origin of Orphan Genes

Orphangenes aregenes thatoccur in specific evolutionary lineages without similarity to genes outside of these lineages and have, therefore, alternatively been named taxonomically restricted genes. They were so far considered to emerge through duplication–divergence processes,but it isnow becomingclear that they canalso arise de novo out of noncoding deoxyribonucleic acid (DNA). This latter proc...

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The gene content of any genome is a rich mosaic of genes that have originated at different times during evolution. Among the most interesting properties related to gene age is the fact that younger genes tend to show accelerated evolutionary rates with respect to older genes. Here, we use a large number of closely related mammalian genomes to gain further insights into the relationship between ...

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ژورنال

عنوان ژورنال: Proceedings of the National Academy of Sciences

سال: 1997

ISSN: 0027-8424,1091-6490

DOI: 10.1073/pnas.94.15.7698